Hepatoprotective pyrrole derivatives of Lycium chinense fruits.
نویسندگان
چکیده
As a part of our search for hepatoprotective compounds from Lycium chinense fruits, three new pyrrole derivatives (1-3) were isolated. These compounds and a related synthetic methylated compound (4) were evaluated for their biological activity and structure-activity relationship, and compounds 1 and 2 showed hepatoprotective effects comparable to silybin at the concentration of 0.1 microM (64.4 and 65.8%, respectively).
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ورودعنوان ژورنال:
- Bioorganic & medicinal chemistry letters
دوره 13 1 شماره
صفحات -
تاریخ انتشار 2003